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Gene regulation that occurs on the order of large chromosomal segments has also been assessed using transgenic mouse approaches with large DNA constructs containing multiple gene sequences such as BAC (Bacterial Artificial Chromosomes (≥100kb) or YAC (Yeast Artificial Chromosomes (≥500-1000kb))
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[Google Scholar] 82.Shan J, Ouyang X, Yang H, Wei R, Liu Y, Zhong G, Liu H, Zhu J