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Melatonin demonstrates oncostatic efficacy in hepatocellular carcinoma (HCC) through dual-pathway modulation: suppressing NF-κB transcriptional activation while attenuating TNF-α-mediated proinflammatory cascades (Ozturk et al., 2023)
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Furthermore, the impact of OS on intracellular signaling pathways such as the mitogen-activated protein kinase (MAPK) and c-Jun N-terminal kinase (JNK) pathways were also validated
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