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Together with selenium, it enables the formation of the phospholipid hydroperoxide glutathione peroxidase enzyme
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Probenecid has also been shown to prevent intracellular depletion of GSH via inhibition of multidrug resistance-associated protein 1 (MRP1/ ABCC1 )–mediated export of GSH, oxidized glutathione (GSSG), and glutathionylated substrates and xenobiotics [44]