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A 2025 systematic review of the orthopedic literature noted that the compound has no approved indication and found that the evidence base remains overwhelmingly preclinical
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[DOI] [PMC free article] [PubMed] [Google Scholar] Becker B., Holtgrefe S., Jung S., Wunrau C., Kandlbinder S., Baier M., Dietz K.J., Backhausen J.E., Scheibe R