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Pharmaceutical companies have invested hundreds of millions of dollars in developing disease-modifying drugs, including monoclonal antibodies, inhibitors (e.g., aducanumab, donanemab, donepezil, memantine), while neurologists, psychiatrists, foundations, families, and affected individuals continue to await a transformative therapeutic breakthrough (Knopman et al., 2021)
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Aging lens epithelium is susceptible to ferroptosis